GPS/INS Integration Accuracy Enhancement Using the Interacting Multiple Model Nonlinear Filters

In this paper, performance evaluation for various single model nonlinear filters and nonlinear filters with interactingmultiple model (IMM) framework is carried out. A high gain (high bandwidth) filter is needed to response fast enoughto the platform maneuvers while a low gain filter is necessary to reduce the estimation errors during the uniformmotion periods. Based on a soft-switching framework, the IMM algorithm allows the possibility of using highly dynamicmodels just when required, diminishing unrealistic noise considerations in non-maneuvering situations. The IMMestimator obtains its estimate as a weighted sum of the individual estimates from a number of parallel filters matchedto different motion modes of the platform. The use of an IMM allows exploiting the benefits of high dynamic models inthe problem of vehicle navigation. Simulation and experimental results presented in this paper confirm theeffectiveness of the method

Evaluation on the Effects of Deicing Chemicals on Soil and Water Environment

AbstractDeicing chemicals are widely used to clear the pavement snow in the cold areas of China and many other countries in winter, because of their simple operation and excellent snow-melting effect, which leads to more convenience for traffic and low probability of traffic accident in the city, especially in metropolis. However, with the ever-growing application of deicing chemicals, their negative effects on environment such as soil and water system increased dramatically. Based on the related researches in China and abroad, this paper summarized the two categories of deicing chemicals and their working principles, and then provided the unique characteristics of deicing chemicals’ effects on soil and water environment in large cities, which may need considerable quantity of the chemicals to relieve traffic congestion. What's more, main aspects of impacts by deicing chemicals on regional soil and water environment and the fundamental factors related to the aspects above respectively were generalized, in order to propose a conceptual model to evaluate the harmful effects. Moreover, this paper put forward some suggestions for the further research in this field to fulfill the model, and provided a scientific basis for the pollution prevention of deicing chemicals on urban environment

K_{l 3} and \pi_{e 3} transition form factors

$K_{\ell 3}$ and $\pi_{e 3}$ transition form factors are calculated as an application of Dyson-Schwinger equations. The role of nonanalytic contributions to the quark--W-boson vertex is elucidated. A one-parameter model for this vertex provides a uniformly good description of these transitions, including the value of the scalar form factor of the kaon at the Callan-Treiman point. The $K_{\ell 3}$ form factors, $f_\pm^K$, are approximately linear on $t\in [m_e^2,m_\mu^2]$ and have approximately the same slope. $f_-^K(0)$ is a measure of the Euclidean constituent-quark mass ratio: $M^E_s/M^E_u$. In the isospin symmetric limit: $-f_+^\pi(0)= F_\pi(t)$, the electromagnetic pion form factor, and $f_-^\pi(t)\equiv 0$.Comment: 11 pages (incl. 3 figures), elsart.sty, epsf.st

A REAL TIME MONITORING MODEL OF THE CALCIUM CARBONATE FOULING INDUCTION PERIOD BASED ON THE CONDUCTANCE TITRATION

A new method has been developed to monitor the calcium carbonate fouling induction period (CCFIP) in real time. Based on the conductance titration, this paper investigated the forming process of CCFIP by a staticdynamic combined simulation experiment unit. With the help of titration analysis (that is titrimetry), an accurate definition of CCFIP and the corresponding real time monitoring model were built up. The investigation results show that the proposed model applies not only to measure the CCFIP in real time, but also applies to an investigation of the influence of various factors on the CCFIP

Global Incidence and mortality of oesophageal cancer and their correlation with socioeconomic indicators temporal patterns and trends in 41 countries

Oesophageal cancers (adenocarcinomas [AC] and squamous cell carcinomas [SCC]) are characterized by high incidence/mortality in many countries. We aimed to delineate its global incidence and mortality, and studied whether socioeconomic development and its incidence rate were correlated. The age-standardized rates (ASRs) of incidence and mortality of this medical condition in 2012 for 184 nations from the GLOBOCAN database; national databases capturing incidence rates, and the WHO mortality database were examined. Their correlations with two indicators of socioeconomic development were evaluated. Joinpoint regression analysis was used to generate trends. The ratio between the ASR of AC and SCC was strongly correlated with HDI (r = 0.535 [men]; r = 0.661 [women]) and GDP (r = 0.594 [men]; r = 0.550 [women], both p < 0.001). Countries that reported the largest reduction in incidence in male included Poland (Average Annual Percent Change [AAPC] = −7.1, 95%C.I. = −12,−1.9) and Singapore (AAPC = −5.8, 95%C.I. = −9.5,−1.9), whereas for women the greatest decline was seen in Singapore (AAPC = −12.3, 95%C.I. = −17.3,−6.9) and China (AAPC = −5.6, 95%C.I. = −7.6,−3.4). The Philippines (AAPC = 4.3, 95%C.I. = 2,6.6) and Bulgaria (AAPC = 2.8, 95%C.I. = 0.5,5.1) had a significant mortality increase in men; whilst Columbia (AAPC = −6.1, 95%C.I. = −7.5,−4.6) and Slovenia (AAPC = −4.6, 95%C.I. = −7.9,−1.3) reported mortality decline in women. These findings inform individuals at increased risk for primary prevention

Electrical transport studies of quench condensed Bi films at the initial stage of film growth: Structural transition and the possible formation of electron droplets

The electrical transport properties of amorphous Bi films prepared by sequential quench deposition have been studied in situ. A superconductor-insulator (S-I) transition was observed as the film was made increasingly thicker, consistent with previous studies. Unexpected behavior was found at the initial stage of film growth, a regime not explored in detail prior to the present work. As the temperature was lowered, a positive temperature coefficient of resistance (dR/dT > 0) emerged, with the resistance reaching a minimum before the dR/dT became negative again. This behavior was accompanied by a non-linear and asymmetric I-V characteristic. As the film became thicker, conventional variable-range hopping (VRH) was recovered. We attribute the observed crossover in the electrical transport properties to an amorphous to granular structural transition. The positive dR/dT found in the amorphous phase of Bi formed at the initial stage of film growth was qualitatively explained by the formation of metallic droplets within the electron glass.Comment: 7 pages, 6 figure

Electromagnetic form factors of light vector mesons

The electromagnetic form factors G_E(q^2), G_M(q^2), and G_Q(q^2), charge radii, magnetic and quadrupole moments, and decay widths of the light vector mesons rho^+, K^{*+} and K^{*0} are calculated in a Lorentz-covariant, Dyson-Schwinger equation based model using algebraic quark propagators that incorporate confinement, asymptotic freedom, and dynamical chiral symmetry breaking, and vector meson Bethe-Salpeter amplitudes closely related to the pseudoscalar amplitudes obtained from phenomenological studies of pi and K mesons. Calculated static properties of vector mesons include the charge radii and magnetic moments: r_{rho+} = 0.61 fm, r_{K*+} = 0.54 fm, and r^2_{K*0} = -0.048 fm^2; mu_{rho+} = 2.69, mu_{K*+} = 2.37, and mu_{K*0} = -0.40. The calculated static limits of the rho-meson form factors are similar to those obtained from light-front quantum mechanical calculations, but begin to differ above q^2 = 1 GeV^2 due to the dynamical evolution of the quark propagators in our approach.Comment: 8 pages of RevTeX, 5 eps figure

Novel use of activated carbon fabric to mitigate smoke taint in grapes and wine

Published online 27 February 2022Background and Aims: Grapegrowers and winemakers, around the world, are searching for strategies to mitigate the compositional and sensory consequences of grapevine exposure to smoke from wildfires. This study evaluated the use of activated carbon fabrics as protective coverings to mitigate the uptake of smoke-derived volatile phenols by grapes, and accordingly, the intensity of smoky, ashy characters in wine. Methods and Results: Smoke was applied toMataro grapes, with and without individual bunches being enclosed in bags made fromthree activated carbon fabrics (felt, light cloth and heavy cloth). Winemade fromsmoke-exposed grapes had an elevated concentration of volatile phenols, but the composition ofwinesmade fromgrapes protected by activated carbon fabric was comparable to that of the Control wine; the difference in concentration of guaiacol, o- andm-cresol and/or syringolwas only 1 μg/L. Winemade from smoke-exposed grapes had diminished fruit and prominent smoke characters, whereas the sensory profile of the wines corresponding to activated carbon fabric treatments could not be differentiated from that of the Control wine. Analysis by GC/MS of the activated carbon fabrics following repeated smoke exposure confirmed their adsorption of smoke volatiles. Conclusions: The activated carbon fabrics successfully protected Mataro grapes and wine from being tainted by smoke exposure. Significance of the Study: This study demonstrates a promising new technology for overcoming smoke taint, an issue of major concern for grape and wine producers worldwide.K.L. Wilkinson, R. Ristic, C. Szeto, D.L. Capone, L. Yu and D. Losi

Insulin Response Genes in Different Stages of Periodontal Disease

Bacterial infections are known to alter glucose metabolism within tissues via mechanisms of inflammation. We conducted this study to examine whether insulin response genes are differentially expressed in gingival tissues, comparing samples from experimental gingivitis and periodontitis subjects to those from healthy individuals. Total RNA was extracted from gingival biopsies from 26 participants: 8 periodontally healthy, 9 experimental gingivitis, and 9 periodontitis subjects. Gene expression patterns were evaluated with a polymerase chain reaction array panel to examine 84 candidate genes involved with glucose metabolism, insulin resistance, and obesity. Array data were evaluated with a t test adjusted by the false discover rate (P < 0.05), and ingenuity pathway analysis was performed for statistical testing of pathways. Although tissue samples were not sufficient to enable protein quantification, we confirmed the upregulation of the key gene using lipopolysaccharide-stimulated primary gingival epithelial cells by Western blot. The mRNA expression patterns of genes that are associated with insulin response and glucose metabolism are markedly different in experimental gingivitis subjects compared with healthy controls. Thirty-two genes are upregulated significantly by at least 2-fold, adjusted for false discover rate (P < 0.05). Periodontitis subjects show similar but attenuated changes in gene expression patterns, and no genes meet the significance criteria. Ingenuity pathway analysis demonstrates significant activation of the carbohydrate metabolism network in experimental gingivitis but not in periodontitis. G6PD protein increases in response to lipopolysaccharide stimulation in primary gingival epithelial cells, which is in the same direction as upregulated mRNA in tissues. Acute gingival inflammation may be associated with tissue metabolism changes, but these changes are not evident in chronic periodontitis. This study suggests that acute gingival inflammation may induce localized changes that modify tissue insulin/glucose metabolism

PD1-based DNA vaccine amplifies HIV-1 GAG-specific CD8+ T cells in mice

Viral vector-based vaccines that induce protective CD8+ T cell immunity can prevent or control pathogenic SIV infections, but issues of preexisting immunity and safety have impeded their implementation in HIV-1. Here, we report the development of what we believe to be a novel antigen-targeting DNA vaccine strategy that exploits the binding of programmed death-1 (PD1) to its ligands expressed on dendritic cells (DCs) by fusing soluble PD1 with HIV-1 GAG p24 antigen. As compared with non-DC-targeting vaccines, intramuscular immunization via electroporation (EP) of the fusion DNA in mice elicited consistently high frequencies of GAG-specific, broadly reactive, polyfunctional, long-lived, and cytotoxic CD8+ T cells and robust anti-GAG antibody titers. Vaccination conferred remarkable protection against mucosal challenge with vaccinia GAG viruses. Soluble PD1-based vaccination potentiated CD8+ T cell responses by enhancing antigen binding and uptake in DCs and activation in the draining lymph node. It also increased IL-12-producing DCs and engaged antigen cross-presentation when compared with anti-DEC205 antibody-mediated DC targeting. The high frequency of durable and protective GAG-specific CD8+ T cell immunity induced by soluble PD1-based vaccination suggests that PD1-based DNA vaccines could potentially be used against HIV-1 and other pathogens.published_or_final_versio